Dedoplistsqaro (also spelled Dedoplistskaro) is a town in the Kakheti region of eastern Georgia. It is located on the Shiraki Plain and serves as the administrative center of the eponymous municipality and district. The town had a population of 5,772 people living in 1,995 households, the majority of whom are ethnic Georgians.
The municipality is bordered to the southeast by Azerbaijan and to the northwest by Signagi Municipality. Dedoplistsqaro's position on the Shiraki Plain places it in the drier, more open landscape characteristic of Georgia's far eastern lowlands, near the country's border with Azerbaijan.