Guamúchil is a city situated in the state of Sinaloa in northwestern Mexico. It is positioned approximately 100 km north of Culiacán, which serves as the state capital. The city functions as the seat of the municipality of Salvador Alvarado.
As the economic and sociocultural center of the Évora Valley Region, the city is named after the local Évora river. In 2010, Guamúchil had a population of approximately 72,500 inhabitants, making it the fifth-largest city in the state following Culiacán, Mazatlán, Los Mochis, and Guasave.