Domingo Arenas was a Mexican revolutionary from the state of Tlaxcala who rose to prominence during the Mexican Revolution. Born in the Nahua community of Zacatelco, he worked as a farmer, shepherd, bread salesman, and factory worker before joining the forces of Francisco I. Madero. Following Madero's fall, Arenas joined the Zapatistas and signed the Plan de Ayala.
Arenas eventually switched sides to support Venustiano Carranza against Emiliano Zapata due to dissatisfaction with how the Zapatistas treated the local population of Tlaxcala. At the height of their influence, his followers, known as Arenistas, controlled much of Tlaxcala and southern Puebla. He was killed in 1916 by Zapatista general Gildardo Magaña during a botched parlay.
The municipality of Domingo Arenas is named in honor of the revolutionary figure. The location serves as a historical landmark reflecting his significant role in the regional conflicts of the early 20th century.