Santa Ana Tlapacoyan is a town and municipality located in the state of Oaxaca in south-western Mexico. It is situated within the Zimatlán District, which lies in the western portion of the Valles Centrales Region.
The municipality occupies a specific area within this region of Oaxaca. While it serves as a local administrative division, its primary geographical context is defined by its placement within the broader cultural and regional landscape of the Valles Centrales.