Santiago Tangamandapio, commonly referred to as Tangamandapio, is a municipality located in the Mexican state of Michoacán. It is situated at the geographic coordinates of 19° 57' North latitude and 102° 26' West longitude.
The municipality is positioned approximately 165 km from Morelia, which serves as the state capital. The administrative area of Tangamandapio also encompasses the community of Tarécuato.