Santo Domingo, alternatively known as Santo Domingo del Mérida, is a city located in Mérida State in Venezuela. The city serves as the municipal seat of Cardenal Quintero Municipality, making it an administrative center for the region.
As the capital of its municipality, Santo Domingo functions as a local governmental hub for Cardenal Quintero Municipality. The city is situated in the Andean region of northwestern Venezuela, characterized by the geography typical of Mérida State.