Cambridge is a city situated in Guernsey County, Ohio, within the United States. It serves as the county seat and functions as the principal city of the Cambridge micropolitan area.
Geographically, the city is located in the Appalachian Plateau region of the Appalachian Mountains in southeastern Ohio. It is positioned adjacent to the intersection of Interstates 70 and 77. According to the 2020 census, the population of the city was 10,089.