Panama City is a city in Bay County, Florida, and serves as the county seat. Located along U.S. Highway 98, it is the largest city in the region between Tallahassee and Pensacola. According to the 2020 United States census, Panama City had a population of 32,939.
Panama City is the most populous city in Bay County and functions as a principal city of the Panama City–Panama City Beach, Florida Metropolitan Statistical Area, which encompasses approximately 200,534 residents. The metro area's larger population reflects the broader regional economy centered around the Panama City area.