Lake City is a statutory town in Hinsdale County, Colorado, United States. It is the county seat, the most populous community, and the only incorporated municipality in the county. The population was 432 at the 2020 census.
The town is located in the San Juan Mountains, in a valley formed by the convergence of Henson Creek and the headwaters of the Lake Fork of the Gunnison River, about seven miles (11 km) east of Uncompahgre Peak, a Colorado fourteener. It is named after nearby Lake San Cristobal.
The area lies at the southern end of the Colorado Mineral Belt. When rich mineral deposits were discovered, the native population was pushed from their tribal lands, and the town of Lake City was incorporated in 1873.