Comerío is a town and municipality located in the center-eastern region of Puerto Rico. Positioned north of Aibonito and south of both Naranjito and Bayamón, it lies east of Barranquitas and west of Cidra and Aguas Buenas. The municipality is administratively divided into seven barrios plus Comerío Pueblo, the main urban center.
As part of the San Juan-Caguas-Guaynabo Metropolitan Statistical Area, Comerío is integrated into the larger metropolitan region of the island's northern coastal region.