San Francisco is a city located in the Caraga region of Mindanao in the southern Philippines. It is situated in Surigao del Sur province, in the easternmost part of the island.
The city serves as a local administrative and commercial center for its municipality. Like other cities in the Caraga region, it has a tropical climate and is part of the Philippines' broader economic zones focused on agriculture, fishing, and small-scale commerce typical of eastern Mindanao.