Lugulu is a market centre in Butula Constituency, Busia County, Kenya. It serves the surrounding neighbourhoods of Esibembe to the north, Bwaliro to the northeast, and Bulwani to the east.
The settlement lies on the road that connects Butula Constituency with the settlement of Nambale. The largest group of residents consists of the Luhya tribe.
Lugulu constitutes a ward, whose current Member of County Assembly is Josephat Wandera, elected in the 2022 general elections.