Brunello is a comune (municipality) in the Province of Varese, in the Italian region of Lombardy. It is located about 45 kilometres (28 mi) northwest of Milan and about 6 kilometres (4 mi) southwest of Varese.
As of 31 December 2004, Brunello had a population of 1,006. The comune covers an area of 1.6 square kilometres (0.62 sq mi), making it one of the smaller municipalities in the province by land area.