Brione is a comune in the province of Brescia, in the Lombardy region of northern Italy. It is one of the many small municipalities that make up the administrative fabric of the province, which is centred on the city of Brescia in eastern Lombardy.
As a comune, Brione forms the basic unit of local government in Italy, with its own municipal administration. The province of Brescia is the largest in Lombardy by area and contains a large number of such comuni, ranging from sizable towns to small communities.
Beyond its status as a comune in the province of Brescia, little further detail is available in the source material. It should not be confused with other places bearing the name Brione, including the municipality of Brione in the Swiss canton of Ticino and the former comune of Brione in the province of Trento.