Cerignale is a comune (municipality) in the Province of Piacenza, in the Italian region of Emilia-Romagna. It is located about 160 kilometres (99 mi) west of Bologna, the regional capital, and about 50 kilometres (31 mi) southwest of Piacenza, the provincial capital.
The comune covers an area of 31.5 square kilometres (12.2 sq mi). As of 31 December 2004, it had a population of 197, making it a small and sparsely populated municipality within the province.