Cenlle is a municipality in the province of Ourense, within the autonomous community of Galicia in northwestern Spain. It belongs to the comarca (district) of O Ribeiro, a wine-producing area in the valley of the Miño river.
As a Galician municipality, Cenlle forms part of the region's dense network of small administrative units, situated inland in Ourense province near the border with Portugal. The surrounding Ribeiro district is historically associated with its vineyards and wine production.