Zarza de Montánchez is a municipality in the province of Cáceres, in the Extremadura region of western Spain. It is situated in the Sierra de Montánchez area, a mountainous comarca within the province.
According to the 2006 census conducted by Spain's National Statistics Institute (INE), the municipality had a population of 631 inhabitants. This figure reflects the small, rural character typical of settlements in this part of Extremadura.