Cristóbal de la Sierra is a village and municipality in the province of Salamanca, in western Spain. It forms part of the autonomous community of Castile and León.
The municipality is described as large in area, while the settlement itself is a village, meaning its resident population is concentrated in a small built-up core within a much more extensive municipal territory. It lies in the western part of Salamanca province, a region of Spain that borders Portugal to the west.
As a municipality, Cristóbal de la Sierra is one of the many small administrative units that make up the Salamanca province, each with its own local council. The village setting reflects the pattern of rural settlement common across this part of Castile and León, where numerous small communities are spread across a sparsely populated countryside.