Cantalpino is a village and municipality in the province of Salamanca, in western Spain. It forms part of the autonomous community of Castile and León.
The municipality lies about 30 kilometres (19 miles) from the city of Salamanca, the provincial capital. It covers an area of 78.47 square kilometres (30.30 square miles).
As of 2016, Cantalpino had a population of 927 people.