Cabezón de Valderaduey is a municipality in the province of Valladolid, in the autonomous community of Castile and León, Spain. It lies in the northern part of the Iberian Peninsula, within the broad plateau region of Castile.
The municipality is small and sparsely populated. According to the 2004 census carried out by Spain's National Statistics Institute (INE), it had a population of 53 inhabitants. Its name derives from the nearby Valderaduey river, a tributary of the Duero, which flows through this part of Castile and León.
Like many rural municipalities in the province of Valladolid, Cabezón de Valderaduey is characterised by its small size and low population density, typical of the depopulated countryside of inland Spain.