Portillo de Toledo is a village and municipality in the province of Toledo, in the Castile-La Mancha region of Spain. It lies within the comarca of Torrijos, roughly 30 kilometres northwest of the city of Toledo.
The municipality had a population of 2,308 inhabitants in 2023, according to official figures. Like many settlements in the surrounding Toledan countryside, it is a small, compact community whose economy has traditionally been tied to agriculture.
Its name distinguishes it from other places called Portillo, and its location in the province of Toledo places it within easy reach of the regional capital, a UNESCO World Heritage city noted for its medieval and Renaissance monuments.