Lupiana is a municipality in the province of Guadalajara, within the autonomous community of Castile-La Mancha, Spain. It is a small rural settlement in the central part of the country, located in the comarca of La Alcarria, a region known for its rolling terrain and agricultural landscape.
According to the 2004 census carried out by Spain's National Statistics Institute (INE), the municipality had a population of 227 inhabitants. This figure reflects the modest size typical of many villages in the sparsely populated rural areas of inland Spain.
Lupiana is best known for the Monastery of San Bartolomé, a historic Hieronymite foundation that stands in the municipality and is one of the notable monuments of the Guadalajara province. The village's small population and its historic religious architecture make it representative of the quiet, heritage-rich settlements found throughout Castile-La Mancha.