Loporzano is a municipality in the province of Huesca, in the Aragon region of northeastern Spain. It is located in the comarca of Hoya de Huesca, in the foothills of the Pyrenees, a short distance east of the city of Huesca.
The municipality covers a large rural area and includes several small settlements, or núcleos, in addition to the main village of Loporzano. As of 2010, the municipality had a population of 540 inhabitants.
Loporzano is known for the Santuario de la Virgen de la Fuente, a sanctuary situated in the municipality, and for the ruins of the Castillo de Montearagón, a medieval fortress and monastery founded in the eleventh century on a hill within the municipal territory.