Grisén is a municipality in the province of Zaragoza, within the autonomous community of Aragon, Spain. It is located in the Ebro river valley area of northeastern Spain, in the comarca of Ribera Alta del Ebro.
According to the 2004 census conducted by the Instituto Nacional de Estadística (INE), the municipality had a population of 477 inhabitants. Like many small municipalities in rural Aragon, Grisén is characterized by a modest population size and a setting typical of the region's agricultural landscape.
The town lies within the province of Zaragoza, whose capital city of the same name is the largest urban centre in Aragon and serves as the provincial administrative hub. Grisén's small population and rural character place it among the many minor municipalities that make up the sparsely populated interior of the region.