Alcaine is a municipality in the province of Teruel, in the autonomous community of Aragon, Spain. It is a small, sparsely populated settlement in this inland region of northeastern Spain.
According to the 2004 census carried out by the Instituto Nacional de Estadística (INE), the municipality had a population of 65 inhabitants. This figure reflects the very small scale of the community and its rural character.
As a municipality of Teruel province, Alcaine forms part of the administrative structure of Aragon, one of Spain's seventeen autonomous communities.