Grandas de Salime is a municipality in the Autonomous Community of the Principality of Asturias, Spain. It lies in the western part of the region, near the border with Galicia.
The town is known for its hydroelectric dam across the Navia River, which forms the Embalse de Salime reservoir.
Grandas de Salime is also a stop along the Camino Primitivo route of the Camino de Santiago. It marks the last stretch of Asturian land before the path enters Galicia through the Acebo Pass.