São Domingos is a city located in the São Domingos region of Cabo Verde, an island nation off the west coast of Africa. The municipality is situated on the island of Santiago, the largest island in the Cabo Verde archipelago.
As a settlement in Cabo Verde, São Domingos is part of the country's administrative divisions. The region has historical significance within the archipelago's development, though detailed information about the specific city's characteristics and current infrastructure remains limited in readily available sources.