San Antonio is a municipality located in the Tolima Department of Colombia, situated in the Andean region of the country. It is part of the administrative divisions of Tolima, one of Colombia's departments in the central-western portion of the nation.
Like many municipalities in the Tolima region, San Antonio is characterized by the mountainous terrain typical of Colombia's Cordillera Central. The municipality functions as a local administrative and commercial center for the surrounding area, serving as part of the broader economic and social fabric of the Tolima Department.