San Carlos is a town and municipality in the Colombian department of Antioquia, forming part of the subregion of Eastern Antioquia. It is located in the Andean interior of northwestern Colombia, within the mountainous terrain characteristic of the department.
The municipality is known as the hydro-electrical capital of Colombia, owing to the presence of numerous dams within its territory and its substantial contribution to the country's energy production. This concentration of hydroelectric infrastructure is its most distinctive feature.
San Carlos had a population of 14,480 at the 2018 census.