San Andrés is a town and municipality in Antioquia Department, Colombia. It is located in the sub-region of Northern Antioquia, in the northwestern part of the country.
The municipality is one of the settlements that make up the northern Antioquian sub-region, an area of Antioquia Department that lies north of the departmental capital, Medellín. Like other municipalities in the department, San Andrés is administered as a municipality, with the town of San Andrés serving as its urban centre.
San Andrés shares its name with several other places in Colombia and the wider region, including the well-known Caribbean archipelago of San Andrés, Providencia and Santa Catalina. The Antioquian municipality is a distinct entity located inland in the department of Antioquia.