San Antonio is a port city and commune in the Valparaíso Region of Chile, serving as the capital of San Antonio Province. It has emerged as the primary freight port of Chile, surpassing the historically important port of Valparaíso during the 21st century.
The city functions as a major hub for the fishing industry along the Chilean coast, anchoring a fishing area that extends from Rocas de Santo Domingo to Cartagena. This combination of freight and fishing operations has established San Antonio as a key economic center for both domestic and international trade.