Villa Krause is a city in the province of San Juan, Argentina, in the Cuyo region of the country's west. It lies in the Rawson department, east of the San Juan River, at an elevation of about 650 metres above mean sea level.
According to the 2001 census (INDEC), the city had a population of around 107,000. Its position east of the San Juan River places it within the broader urban area centred on the provincial capital, San Juan.