Tunuyán is a city in the west of Mendoza Province, Argentina, situated on the western shore of the Tunuyán River. It lies about 80 km (50 mi) south of the provincial capital, Mendoza, and roughly 100 km (62 mi) east of the border with Chile. With a population of 49,132, it is the head town of the Tunuyán Department.
Together with the Tupungato Department and the San Carlos Department, Tunuyán forms part of the Valle de Uco region. The area is known within the Argentine wine industry for its significant and modern vineyards and wineries.
Since the turn of the millennium, investment attracted by the region's combination of climate, soil, and altitude has transformed the area. This has made it one of Argentina's most important regions for high-quality wine production, along with the enotourism that accompanies it.