Matsulu is a township located in South Africa within the Mpumalanga province. It falls under the jurisdiction of the Mbombela Local Municipality and the Ehlanzeni District Municipality.
The township is situated between Kruger National Park and the N4 national road, approximately 41 kilometres east of Mbombela. It is positioned 3 kilometres before the Kaapmuiden train station and is bordered by the Nsikazi River to the east and the Crocodile River to the south.