San Carlos del Zulia is a city located in the Zulia State of Venezuela. It serves as the capital of the Colón Municipality.
The city was founded on March 14, 1778, by Captain Nicolás José Antúnez Pacheco y de la Cruz y Velasco, an alderman from the city of Maracaibo. He was accompanied by Lieutenant Ramón Hernández de la Calle, who was tasked with the pacification of the Motilón Indians inhabiting the region.