Seguin is a city located in the United States. The name itself has various etymological origins, including French, Gascon, and potentially Frankish roots of Germanic origin.
The name is associated with several historical variants such as Seghin, Sigiwinus, Siguvinus, Siguinus, Siguin, Sigiwin, Sigwin, Sigoin, and Segouin. According to Jean de Jaurgain's citation of Saint Andrew of Bordeaux, the original Vascon name written in Latin was Sihiminum, which is related to the Basque term Seme(no) meaning "son." Other historical spellings include Scimin, Skimin, Scemenus, Semen, Semeno, Xemen, and Ximen, the latter of which gave rise to the Castilian names Ximeno and Jimeno.