Murrysville is a home rule municipality situated in Westmoreland County, Pennsylvania, within the United States. Located approximately 20 miles east of Pittsburgh along U.S. Route 22, it serves as one of the larger communities in its county and is part of the broader Pittsburgh metropolitan area.
As of the 2020 United States census, Murrysville had a population of 21,006 residents. The municipality functions under home rule status, providing local governance for its community within the western Pennsylvania region.