Loup City is a city located in Sherman County, Nebraska, in the United States. It serves as the county seat for the region and holds the distinction of being the first permanent settlement established within the county.
As of the 2020 census, the population of Loup City was 1,053 residents. The city is situated near the Middle Loup River and is located approximately 5 miles (8.0 km) from Sherman Reservoir.