Keytesville is a city located in Missouri, United States. It serves as the county seat of Chariton County and has a population of 440 residents according to the 2020 census.
The city is notable for its historical connections to military figures. It is the hometown of U.S. Army General Maxwell D. Taylor, who led the 101st Airborne division during the Normandy invasion in World War II. Additionally, Confederate General Sterling Price, who conducted an unsuccessful cavalry raid through his home state and attacked Keytesville, previously operated a hotel in the city.