Louisville is a city located in the U.S. state of Kentucky. It serves as the most populous city in the state and ranks as the sixth-most populous city in the Southeast region. Nationally, it is the 27th-most-populous city in the United States.
The city is situated on the Indiana state line and has served as the historical county seat of Jefferson County; since 2003, it has been the nominal seat of that county. By land area, Louisville is the 24th-largest city in the country, though it ranks as the 265th most dense city by population density.