Opelika is a city located in the east-central part of Alabama in the United States. It serves as the county seat of Lee County and is recognized as a principal city within the Auburn-Opelika Metropolitan Area.
According to the 2020 census, Opelika has a population of 30,995, representing a 17.1 percent increase from the 26,477 residents recorded in 2010. The city is part of the Greater Columbus combined statistical area, which includes the Auburn-Opelika and Columbus, Georgia metropolitan areas.