Kotzebue, also known as Qikiqtaġruk, is a city located in the Northwest Arctic Borough of Alaska in the United States. It serves as the seat of the borough and stands as its largest community.
The city functions as the primary economic and transportation hub for the surrounding subregion of Alaska. As of the 2020 census, Kotzebue had a population of 3,102 residents, reflecting a slight decrease from the 3,201 people recorded in 2010.