Oğuzeli is a municipality and district located in the Gaziantep Province of Turkey. Covering an area of 689 km2, it has a population of 36,644 as of 2025. It ranks as the sixth most populated district in Gaziantep, characterizing it as one of the smaller, more rural districts in the province alongside Araban, Karkamış, Nurdağı, and Yavuzeli.
The district serves as a suburban area situated just southeast of the urban centers of Şehitkamil and Şahinbey. Its municipal center is located near the border of Hasan Kalyoncu University at the edge of Şahinbey. Large portions of the district are dedicated to agricultural farms, which are primarily utilized for the cultivation of pistachios.