İscehisar is a town and the seat of the İscehisar District in Turkey. It is located within the Afyonkarahisar Province in the Aegean region, situated on the road connecting the city of Afyon with Ankara.
As of the 2024 census, the district has a total population of 25,084. The current mayor of İscehisar is Seyhan Kılınçarslan of the AKP.