Khlong Sam Wa is one of the 50 districts (khet) located in Bangkok, Thailand. It serves as a significant administrative area within the capital city's urban layout.
The district is bordered by several other areas, including the Lam Luk Ka district of Pathum Thani province to the north, and the Bangkok districts of Nong Chok, Min Buri, Khan Na Yao, Bang Khen, and Sai Mai. As of 2022, Khlong Sam Wa was recorded as having the highest population of all districts in Bangkok.