Orekhovo-Borisovo Severnoye, commonly referred to as Orekhovo-Borisovo, is a district located in the Southern Administrative Okrug of Moscow, Russia. The area covers a total size of 7.540 square kilometres (2.911 mi2) and was developed on the site of several former villages, including Orekhovo, Borisovo, Shipilovo, Zyablikovo, and Brateyevo.
Mass housing construction in the region began in the early 1970s, leading to the establishment of a microdistrict. The district's primary landmark is the Orekhovo-Borisovo Cathedral.