Caazapá is a city located in the Caazapá Department of Paraguay. It serves as the capital of the department and was founded in 1607 by Friar Luis de Bolaños.
The city is organized into five neighborhoods known as "Barrios." These include Barrio San Pablo, which is the main neighborhood, as well as Barrio Santa Teresita, Barrio San Blás, Barrio San Antonio, and Barrio San Roque. The latter contains the original Chapel built by Franciscans during the Spanish rule in Paraguay.
The Franciscan mission at Caazapá is recognized as an important event within Paraguayan cultural heritage.