El Macano is a corregimiento located in the Guararé District within the Los Santos Province of Panama. It serves as a local administrative division characterized by its rural setting in the country's interior.
Demographic data indicates that the population of El Macano has fluctuated over recent decades. As of 2010, the area had a population of 281 residents, following a previous count of 339 in 1990 and 242 in 2000.