Boca de Cupé is a corregimiento located in the Pinogana District of the Darién Province in Panama. It serves as a local administrative division within the country's southeastern region.
As of the 2010 census, the population of Boca de Cupé was 1,167 residents. Historical data indicates steady growth over the preceding decades, with recorded populations of 901 in 1990 and 902 in 2000.