Chiriquí Grande is a corregimiento located in the Chiriquí Grande District of the Bocas del Toro Province in Panama. It serves as the administrative seat of the district and is situated on the southern shore of the Chiriquí Lagoon.
The area covers a landmass of 58.8 square kilometres (22.7 sq mi). As of the 2010 census, the population was recorded at 3,014 people, resulting in a population density of approximately 51.2 inhabitants per square kilometre. The town is notable for its port, which functions as the northern terminus of the Trans-Panama pipeline.